姓名:罗海芸教授博士生导师
职务:支部书记
研究方向:脑缺血相关机制及药物治疗
个人简介:
长期致力于脑缺血发病机制和抗脑缺血药物机制或新型抗脑缺血药物研发的研究,取得成果。包括发现三七皂苷Rb1治疗脑缺血的新机制和proBDNF在脑缺血中的神经毒性作用,提出相应新型内源性生物活性因子治疗脑缺血.。先后主持省级重点项目及面上项目情况。目前近5年以通讯/共同通讯、第一/共同第一作者发表SCI论文8篇;任Brain Research期刊审稿人。
个人简历:
2021/8至今,bat365在线平台,基础医学院药理学系,教授,博导
2018/10-2021/8,bat365在线平台,基础医学院药理学系,教授
2015/6月-2016/7月澳大利亚南澳大学,神经药理学研究所,访问学者
2013/4,bat365在线平台,基础医学院药理学系,副教授,硕导
2008/10-2018/10 ,bat365在线平台,基础医学院药理学系,副教授
2004/09-2007/06,bat365在线平台,基础医学院病理生理学,博士
2001/10-2008/9,bat365在线平台,基础医学院药理学系,讲师
2001/09–2004/06,bat365在线平台,基础医学院生理系,硕士
1996/07-2001/09,bat365在线平台,基础医学院生理学系,助教
1991/09-1996/07,bat365在线平台,临床医学专业,学士
承担科研项目情况:
省部级科研项目
1.云南省自然科学基金重点项目,2019FA031, proBDNF及其受体在脑缺血中的神经毒性作用及多靶点作用机制研究, 2019/7-2022/6,50万,在研,主持
2.云南省自然科学基金-bat365在线平台联合专项,2017FE467-163,三七皂苷Rb1后适应对海马缺血微环境的影响及可能信号转导机制研究,2017/01-2020/12,10万元,在研,主持
代表性论著:
1、 期刊论文:
(1) Ling Wang, Yue-Qin Zeng, Juan-Hua Gu, Rui Song, Peng-Hui Cang, Yong-Xuan Xu, Xiao-Xia Shao, Li-Jin Pu*, Hai-Yun Luo*, Xin-Fu Zhou*.Novel oral edaravone attenuates diastolic dysfunction of diabetic cardiomyopathy by activating the Nrf2 signaling pathway.Eur J Pharmacol.2022 Feb 22;920:174846.doi: 10.1016/j.ejphar.2022.174846(Corresponding author)
(2) Guo, Ying; Xie, Jianping; Zhang, Lanchun; Yang, Lingli; Ma, Jiaqing; Bai, Yufan; Ma, Wenjie; Wang, Ling; Yu, Haofei; ZengYueqin*; LuoHaiyun*; Zhang, Rongping*; Ginsenoside Rb1 exerts antidepressant-like effects via suppression inflammation and activation of AKT pathway, Neuroscience Letters, 2021, 744: 0-135561
(3)Xie, Jianping#; Li, Xia#; LuoHaiyun#; He, Liu; Bai, Yufan; Zheng, Fuyun; Zhang, Lanchun; Ma, Jiaqing; Niu, Zhiqiang; Qin, Yubing; Wang, Ling; Ma, Wenjie; Yu, Haofei; Zhang, Rongping; GuoYing ; Depressive Symptoms, Sleep Quality and Diet During the 2019 Novel Coronavirus Epidemic inChina: A Survey of Medical Students, Frontiers in Public Health, 2021, 8: 0-588578
(4). Yang CY, Yang JY, Xiong YX, Zhuang XF, Su H, Hu S, Ma JQ, Zhou XF, Luo HY (*), Sun J. Panax notoginsenoside Rb1 Restores the Neurotrophic Imbalance Following Photothrombotic Stroke in Rats. Neurotox Res. 2019 Oct;36(3):441-451. doi: 10.1007/s12640-019-00058-2 (Corresponding author)
(5)Luo HY, Rahman M, Bobrovskaya L, Zhou XF. The level of proBDNF in blood lymphocytes is correlated with that in the brain of rats with photothrombotic ischemic stroke. Neurotox Res. 2019 Jul;36(1):49-57. (期刊论文)(Corresponding author)
(6)Yan YT, Li ShD , Luo HY *.Panax notoginsenoside saponins Rb1 regulates the expressions of Akt/ mTOR/PTEN signals in the hippocampus after focal cerebral ischemia in rats. Behavioural Brain Research.2018. 3.6, 345: 83~92(Corresponding author)
(7). Guo Y #, Wang LP #, Li C #, Sun J *, Luo HY *. Effects of ginsenoside Rb1 on expressions of Phosphorylation Akt/Phosphorylation mTOR/Phosphorylation PTEN in artificial abnormal hippocampal microenvironment in rats, Neurochemical Research, 2018, 43(10): 1927-1937(Corresponding author)
(8). Wang S, Li M, Guo Y, Li C, Wu L, Zhou XF, Luo Y, An D, Li S, Luo HY*, PuL.Effects of Panax notoginseng ginsenoside Rb1 on abnormal hippocampal microenvironment in rats. J Ethnopharmacol. 2017, 202:138-146. (Corresponding author)