一、个人简介
罗承良,博士,教授,博导,哈佛医学院博士后。2024年5月以高层次人才从苏州大学引进至bat365在线平台法医学院工作。先后主持国家自然科学基金4项(含面上2项),省部级项目5项,第一作者或通讯作者在Journal of Pineal Research、Free Radical Biology and Medicine、Forensic Science International等知名期刊上发表SCI收录论文40余篇。副主编或参编教材及著作6部。曾获江苏省高校“青蓝工程”优秀青年骨干教师、江苏省科学技术三等奖、全国博管办博士后国际交流计划派出项目获选者等奖励和荣誉。担任海峡两岸医药卫生交流协会法医学分会委员、中国生物物理学会生物微量元素分会委员、国际期刊《Antioxidants》客座主编、《Aging and Disease》与《Brain-X》青年编委等学术兼职。
二、主要研究方向
从事学科方向:法医病理学及法医毒理学,主要研究方向:(1)颅脑损伤认知行为异常机制与生物标志物筛选;(2)损伤与死亡时间推断。
三、近五年主要承担的科研项目
(1)国家自然科学基金地区科学基金项目,82460256,基于MCU介导Ca2+/ROS/铁离子串扰调控铁死亡探讨大麻二酚减轻脑外伤后认知障碍的分子机制,2025.1-2028.12,32万,在研,主持。
(2)国家自然科学基金面上项目, 82271409, 基于线粒体介导铁死亡过程探讨mitoNEET调控Tfr1与Acsl4在脑外伤后认知功能障碍中的作用机制, 2023.01-2026.12, 52万元, 在研, 主持。
(3)国家自然科学基金面上项目, 81971163, 基于TrkB/PI3K/Akt/Nrf2通路探讨NAS改善颅脑创伤后氧化应激与神经功能的作用机制研究, 2020.01-2023.12, 55万元, 已结题, 主持。
(4)bat365在线平台高层次人才引进科研启动基金,K132310405,bat365在线平台高层次人才科研和配套,2024.06-2029.05,200万,在研,主持。
四、近五年代表性成果
[1] Rui T, Wang H, Li Q, Cheng Y, Gao Y, Fang X, Ma X, Chen G, Gao C, Gu Z, Song S, Zhang J, Wang C, Wang Z, Wang T, Zhang M, Min J, Chen X, Tao L*, Wang F*, Luo C*. Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury-induced ferroptosis. Journal Pineal Research 2021; 70(2):e12704. (IF: 12.081)
[2] Cheng Y, Gao Y, Li J, Rui T, Li Q, Chen H, Jia B, Song Y, Gu Z, Wang T, Gao C, Wang Y, Wang Z, Wang F*, Tao L*, Luo C*. TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway. Free Radic Biol Med. 2023; 194:184-198. (IF: 8.101)
[3] Gao Y, Wang T, Cheng Y, Wu Y, Zhu L, Gu Z, Wu Y, Cai L, Wu Y, Zhang Y, Gao C, Li L, Li J, Li Q, Wang Z, Wang Y, Wang F*, Luo C*, Tao L*. Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury. Free Radic Biol Med. 2023; 199:97-112. (IF: 8.101)
[4] Gao Y, Cai L, Wu Y, Jiang M, Zhang Y, Ren W, Song Y, Li L, Lei Z, Wu Y, Zhu L, Li J, Li D, Li G*, Luo C*, Tao L*. Emerging functions and therapeutic targets of IL-38 in central nervous system diseases. CNS Neurosci Ther. 2024; 30(2):e14550. (IF: 5.5)
[5] Qu W, Cheng Y, Peng W, Wu Y, Rui T, Luo C*, Zhang J*. Targeting iNOS Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage via Promoting Ferroptosis of M1 Microglia and Reducing Neuroinflammation. Mol Neurobiol. 2022; 59(5):3124-3139. (IF: 5.59)
[6] Xu Y, Jia B, Li J, Li Q*, Luo C*. The Interplay between Ferroptosis and Neuroinflammation in Central Neurological Disorders. Antioxidants. 2024; 13(4):395. (IF: 6.0)
[7] Jia B, Li J, Song Y, Luo C*. ACSL4-Mediated Ferroptosis and Its Potential Role in Central Nervous System Diseases and Injuries. Int J Mol Sci. 2023; 24(12):10021 (IF: 5.6)
[8] Cheng Y, Qu W, Li J, Jia B, Song Y, Wang L, Rui T, Li Q*, Luo C*. Ferristatin II, an Iron Uptake Inhibitor, Exerts Neuroprotection against Traumatic Brain Injury via Suppressing Ferroptosis. ACS Chem Neurosci. 2022; 13(5):664-675.(IF: 5.0)
[9] Wang Y, Hu G, Liu N, Wang M, Chen R, Zhu R, Wang Y, Ren X, Wang Y, Xu W, Luo C*, Wang J*, Xia S*, Xiu X. Development of Dermestes tessellatocollis Motschulsky under different constant temperatures and its implication in forensic entomology. Forensic Sci Int. 2021;321:110723. (IF: 2.2)
[10] Yao Xu, Yongsheng Liu, Yan Wu, Jingshan Sun, Xiaocheng Lu, Kun Dai, Yiting Zhang*, Chengliang Luo*, Jian Zhang*. Curcumin Alleviates MicrogliaMediated Neuroinfammation and Neuronal Ferroptosis Following Experimental Subarachnoid Hemorrhage by Modulating the Nrf2/HO1 Signaling Pathway. Molecular Neurobiology 2024 Aug. https://doi.org/10.1007/s12035-024 -04443-7 (IF: 4.6)
五、联系邮箱: luochengliang@kmmu.edu.cn